Background: According to the Minister of Health’s decree concerning medical service standards, clinical practice guidelines (CPG) are one of the essential documents to guide healthcare service based on best-available scientific evidence. Throughout the years, a large number of hospital CPGs have been developed in Cipto Mangunkusumo General Hospital, Jakarta, Indonesia. Nevertheless, the quality of the CPGs is yet to be assessed.

Objectives: To develop a critical- appraisal tool that address the government’s requirement for hospital CPG.

Methods: An initial review of the existing appraisal tools was conducted to select the questions to be included in the critical-appraisal tool. Subsequently, a Delphi panel was established to build a consensus for the appraisal tool.

Results: According to MoH’s decree concerning medical service standards, hospital CPGs should comply with 5 domains, i.e. validity, systematic, evidence-based, updated, and clearly written. An initial list of 22 questions, of each was coherent with at least one of the abovementioned domains, was identified through the review of existing appraisal tools. A Delphi panel consisting of methodological and clinical experts was developed and went through two rounds of the Delphi process to refine the initial lists of questions. A consensus of the Delphi panel decided the final hospital CPG appraisal tool consisting of 14 questions.

Conclusions: A critical-appraisal tool addressing 5 important domains for hospital CPG has been developed to ensure the quality of CPGs in Cipto Mangunkusumo General Hospital. The tool can also be used as a guide when initiating CPGs development in the hospital.