Background: Cardiovascular diseases are the leading cause of death and disability in the population of most countries, including Ukraine.

Objectives:To develop up-to-date evidence-based clinical guidelines and protocols of medical care in cardiovascular diseases which will allow harmonisation of Ukrainian practice with international recommendations and quality medical care assistance for the relevant areas.

Methods: At the end of 2014 the multidisciplinary working groups on development of guidelines and protocols on different areas of cardiovascular diseases were approved. According to the results of a systematic literature review conducted in the databases Medline, PubMed, DynaMed, G-I-N etc. ESC, ACCF/AHA and NICE guidelines were selected for adaptation in Ukraine.

Results: During the meetings the working groups discussed the opportunities to meet the guidelines’ recommendations in real conditions in Ukraine. There were debates concerning the possibility of implementation of certain recommendations in Ukraine.The group also considered the issue of new antiplatelet drugs with a high evidence base, which were not registered in Ukraine at this stage. The adapted guidelines for the treatment of acute and chronic coronary artery disease included separate sections with recommendations for revascularisation from 2014 ACCF/AHA guideline, which allows the doctor to stratify patient against the risk of complications and identify high-risk patients who should be given urgent percutaneous coronary intervention. As a result of the work clinical guidelines and unified clinical protocols were prepared, adapted and approved by the Ministry of Health of Ukraine on Acute Coronary Syndromes Without ST Segment Elevation, Stable Coronary Artery Disease, Pulmonary Hypertension, Prevention of Cardiovascular Disease, Dyslipidemia, Heart Failure, and Atrial Fibrillation.

Conclusions: Development of adapted clinical guidelines and unified clinical protocols on cardiovascular diseases is an issue of state concern in the field of public health. The availability of such new up-to-date medical documents is a breakthrough in medical care assistance for these areas.