Meta-analysis of patient-reported outcomes and application of minimal important differences to facilitate interpretation in systematic reviews and guideline development

Session: 

Workshop session 5: Thursday, 14:00-15:30

Workshop category: 

  • Methods for conducting syntheses (including different evidence, searching and information retrieval, statistics, assessing methodological quality)
Status

ID: 

WS40
Date and Location

Date: 

Thursday 14 September 2017 - 14:00 to 15:30

Location: 

Meeting Room 2.43
Contact persons and facilitators

Contact person:

Tahira Devji

Facilitators: 

Tahira Devji
Alonso Carrasco-Labra

Acknowledgements:

Guyatt G1, Patrick D2, Johnston B3, Nesrallah G4
1 McMaster, Canada
2 University of Washington, United States of America
3 The Hospital for Sick Children, Canada
4 Humber River Regional Hospital, Canada
Target audience

Target audience: 

Review authors, guideline developers

Level of difficulty: 

Intermediate
Type of workshop

Type of workshop : 

Training
Abstract

Abstract:

Objectives:
1) Present and apply principles influencing choice of patient-reported outcome measures (PROMs) in systematic reviews.
2) Review the use of minimally important differences (MIDs) in enhancing interpretability of PROMs in systematic reviews.
3) Introduce an instrument for evaluating the credibility of MIDs and apply it to a sample of studies.
4) Help participants apply presentation approaches relying on the MID to make PROMs more interpretable in systematic reviews.

Description:
This workshop will build on a workshop presented earlier at the Summit describing approaches to make PROMs more interpretable in systematic reviews, including those relying on MIDs. This workshop will review the principles governing choice of an outcome measure in systematic reviews. Participants will apply the approach to a data set. Then we will review the concept of the MID and its application to enhance interpretability of reviews. We will then introduce an instrument for evaluating the credibility of MIDs in PROMs and participants will apply the instrument to a data set. Finally, participants will apply the methods for using the MID to enhance interpretability to a data set to generate results in MID units, relative effects, and risk differences.